After finding out that the gene of gravidarians is pure, the uterus should be cleared and followed up timely. 1. Once the diagnosis of genetic purity of gravida is established, the uterus should be cleared in time, after the preparation of infusion and blood preparation, suction and curettage under the guidance of ultrasound should be adopted, the cervical canal should be fully dilated, and a large-sized suction tube should be used to attract, and when most of the tissues are suctioned out the uterus is obviously shrunken, the uterus should be scraped with a spatula, and then the tissues will finally be examined by pathology. 2. Patients with genetically pure hyperemesis gravidarum should measure HCG once a week until three consecutive negative results, and then follow up every month in the first half of the year and every two months in the second half of the year, which includes inquiring about menstruation, hemoptysis, ultrasound and chest X-ray, etc. If hyperemesis gravidarum occurs, it is recommended to go to a doctor in time. In case of hyperemesis gravidarum, it is recommended to go to the hospital in time for the doctor to formulate a treatment plan so as to avoid delaying the condition.