The soreness of one side of the nose may be caused by rhinitis, sinusitis, deviated nasal septum, nasal foreign body, nasal cartilage membrane inflammation or nasal tumor. It is recommended that patients pay attention to the presence of headache, runny nose, nasal congestion and other accompanying symptoms in order to further clarify the diagnosis. 1, rhinitis: can be divided into acute rhinitis and chronic rhinitis, the nasal mucosa is attacked by bacteria, viruses, or dirty air granular material stimulation, so that the nasal mucosa inflammation, inflammatory secretions stimulation caused by one side of the nose sore, some people may also be accompanied by nasal congestion or loss of smell, appearing Some people may also suffer from nasal congestion or loss of sense of smell, clear watery or sticky white or yellow nasal discharge, etc. If it is acute rhinitis, it is usually not serious, drink more warm water and pay attention to rest, it will gradually improve in 2-3 days. If it is chronic rhinitis, you can apply erythromycin ointment in the nasal cavity, you can also take Chinese medicine, such as rhinitis tablets, rhinitis kang tablets, etc. You can usually use a humidifier to keep the nasal mucosa moist; 2. Sinusitis: sinusitis is an inflammation of the mucous membrane of the sinuses, due to inflammation stimulation, patients can have a sore nose on one side, the symptoms are generally more serious than rhinitis, some patients may also be accompanied by headache, dullness or yellow pus nasal discharge, etc. Sinusitis is divided into acute sinusitis and chronic sinusitis, for acute sinusitis is generally based on drug treatment, including the use of nasal rinse, nasal spray drops, etc. Commonly used drugs are levocabastine hydrochloride nasal spray, nasal spray of azelaic acid, budesonide nasal spray, etc. If necessary, oral antibiotics, such as amoxicillin, cefuroxime, etc. Chronic sinusitis can be treated through surgery; 3. Deviated nasal septum: The nasal septum can be deviated to one or both sides, or locally protrude, affecting the physiological function of the nasal cavity. Due to the stimulation of the deviated nasal septum, patients can have the performance of soreness in one side of the nose, in addition to nasal congestion, headache, nasal bleeding and other symptoms. If the patient’s symptoms are obvious, surgery is usually needed; 4. Nasal foreign body: For example, children often stuff foreign bodies into the nasal cavity when playing or out of curiosity, sneezing, vomiting, etc. Food retrograde from the posterior nostril into the nasal cavity can also form a nasal foreign body, insects flying or crawling into the nasal cavity can also become a nasal foreign body. Due to the stimulation of foreign body, the patient may show soreness on one side of the nose, as well as nasal congestion, foul smell in the snot, bleeding nasal mucus and other manifestations. Once a foreign body appears in the nasal cavity, it should be promptly consulted and removed with tweezers after admission; 5. Nasal cartilage periostitis: there is cartilage in the nasal cavity, and when the cartilage membrane is stimulated, local inflammation may form, producing symptoms of soreness in one side of the nose, at which time local hot compresses can be applied to the patient and erythromycin ointment can be applied in the nasal cavity; 6. Nasal tumors: benign tumors include nasal polyps, nasal cysts, hemangiomas, papillomas, etc., malignant tumors including nasopharyngeal cancer, sinus cancer, etc. These benign or malignant tumors may stimulate the surrounding mucous membrane and produce secondary inflammation, resulting in soreness on one side of the nose. At this time, electronic rhinolaryngoscopy needs to be done as soon as possible to clarify the diagnosis. For benign tumors, surgery is performed to remove them, and for malignant tumors, in addition to surgical removal, radiotherapy and chemotherapy are needed before and after surgery. If patients experience soreness on one side of the nose, they should pay attention to avoid adverse stimuli, such as smoke, dust, irritating gas, etc., and pay attention to rest and keep warm. If the symptoms persist without relief, it is recommended to be promptly admitted to the hospital and take the above-mentioned symptomatic treatment measures under the guidance of the doctor according to the cause.