Lower extremity vascular occlusion requires the use of anticoagulant drugs such as aspirin, lipid-adjusting drugs such as atorvastatin, and drugs to improve lower extremity ischemia such as beta prostaglandin sodium, depending on the specific situation.
1. Anticoagulant drugs: before using them, it is necessary to exclude the abnormal coagulation function and the bleeding situation in the body. Representative drugs are aspirin, through antagonizing platelet aggregation, so that the blood of the lower limbs to reduce coagulation. Adverse effects include nausea and vomiting, epigastric discomfort, liver and kidney dysfunction and allergic reactions.
Allergic to aspirin, thrombocytopenia or hemophilia, patients with severe heart failure, those with active bleeding and infants under 3 months of age are prohibited.
2. Lipid-adjusting drugs: generally statins, in the case of their own poor lipid profile or the presence of plaque instability, in the exclusion of liver disease and rhabdomyolysis, can be used. The representative drug is atorvastatin, which allows the risk of thrombosis to be reduced by improving the lipid profile.
Adverse reactions are rhabdomyolysis with myopathy, liver enzyme abnormalities and allergic reactions. Contraindications are active liver disease, hypersensitivity to the drug, pregnancy and lactation.
3. Improvement of lower limb ischemic drugs: the representative drug is cilostazol, which is mainly used for claudication caused by lower limb vascular blockage, and the adverse effects include abdominal pain, palpitation, gastrointestinal symptoms, allergic reactions, etc. Contraindications are allergy to the drug. Contraindications are allergic to the drug, grade 3~4 congestive heart failure, bleeding patients, pregnancy is prohibited.
The use of drugs need to comply with medical advice.