Knee pain is a very common symptom, especially in middle-aged and elderly people with osteoarthritis who are most likely to suffer from pain, followed by dysfunction, which means difficulty moving around. How can we reduce the pain? First, let’s think about where the pain comes from. Pain is the sensation of pain due to inflammatory factors produced by an injury, which stimulates peripheral nerves. So, why is there an injury? Obviously traumatic injuries need not be mentioned, but also some are overweight, and also some degenerative joint degeneration. If an injury has occurred, all that can be done is to repair the injury, which requires transporting the various inflammatory factors that produced the injury, replenishing the new nutrients, and curbing the factors that produced the injury. All of this requires improving the blood circulation in the knee area, and only relatively strong methods of improving local blood circulation can reduce pain and promote repair. Of course, if there is a problem with the relative position of the knee joint, it is still necessary to reset it, and if there is atrophy of the associated muscles, it is still necessary to increase the size and strength of the muscles through exercise. Tui na can improve local blood circulation, but it is basically temporary, as are acupuncture and joint release, so relief can also be temporary. The need for better blood circulation in the lower extremities requires not only external treatment, but also internal treatment. Internal treatment is to take Chinese herbal medicines to nourish the liver and kidneys, warm the meridians and open the veins, invigorate the blood and remove blood stasis, and eliminate dampness and phlegm. Tui na and joint release, as well as acupuncture can be used in conjunction. The treatment of knee pain, especially osteoarthritis in middle-aged and elderly people, should be a comprehensive treatment with more health preaching, etc., to reduce recurrence and improve quality of life.