Cetuximab is an anti-tumor drug, or a targeted tumor therapy drug, which usually works on the target of the tumor. Targeted drugs are more precise in their action and have relatively fewer side effects. Cetuximab is one such targeted anti-tumor drug that works by targeting the specific receptor of interest. The drug acts on the relevant EGF receptor and interacts with the receptor, thus blocking the intracellular signaling pathway, thereby inhibiting the proliferation of cancer cells and causing apoptosis of cancer cells, thus playing an anti-tumor role, so cetuximab is mainly used in the clinical treatment of advanced colorectal cancer. The drug can also be used in combination with other drugs, such as irinotecan, for drug-resistant colorectal cancer treated with irinotecan-based chemotherapy. In conclusion, cetuximab is a targeted drug that can treat tumors more precisely and effectively, and the side effects of this type of targeted therapy drugs are also less compared to other chemotherapy drugs.