Cephalosporin refers to cephalosporins. Taking cephalosporins or amoxicillin for toothache caused by sensitive bacterial infections is fine, and you should choose the right medication according to your specific condition and under the guidance of your doctor. Cephalosporins are antibiotics, commonly cefuroxime, cefaclor, cefixime and so on. Amoxicillin is one of the antibiotic drugs, these two types of drugs belong to the β-lactamase class of antibiotic drugs, able to inhibit the biosynthesis of mucopeptides in the bacterial cell wall by inhibiting the bactericidal, anti-inflammatory effect. Cephalosporins are prohibited for those who are allergic to cephalosporin antibiotics; amoxicillin is prohibited for those who are allergic to penicillin or those with allergies. If a toothache occurs, the patient needs to choose drugs under the guidance of the doctor and according to the patient’s condition. In daily life, you should pay attention to oral hygiene, brush your teeth correctly, and avoid brushing too hard to cause toothache.