The causes of calf soreness are lumbar disc herniation, muscle strain, pear-shaped muscle syndrome, etc., and need to treat the cause of the medication, there is no specific treatment for calf soreness of the drug. 1. For calf soreness caused by lumbar disc herniation, you can take methylcobalamin and other neurotrophic drugs, ibuprofen and other non-steroidal anti-inflammatory drugs as prescribed by the doctor. 2. For calf soreness caused by muscle strain, take muscle relaxants such as epirubicin and non-steroidal anti-inflammatory drugs such as celecoxib as prescribed by the doctor. 3. For the pear-shaped muscle syndrome caused by, can be prescribed oral diclofenac sodium and other non-steroidal anti-inflammatory drugs, local injection dexamethasone and other glucocorticosteroids or lidocaine and other local anesthetic closed treatment. Calf soreness should go to the regular hospital in time, clear cause, under the guidance of the doctor for standardized treatment, not blindly self-medication, so as not to delay the condition.