Whether a positive high-risk HPV51 test will heal on its own depends on the duration of the infection and whether it causes cervical lesions, and needs to be judged in the context of the patient’s specific situation. Usually, if the patient has been infected with high-risk HPV51 positive for a relatively short period of time and has not caused cervical lesions, the patient may heal on his own or with medication; if the infection is longer and has caused cervical lesions, it usually cannot heal on its own and requires timely treatment, and some patients can be cured. High-risk HPV51 positive, the patient’s infection time is relatively short, did not cause cervical lesions, the body immunity is high, the local immune environment of the cervix is normal, most people within 2 years natural turn negative, that is, self-healing, can also apply interferon pessary, promote the turn negative, the chances of cervical lesions will be significantly reduced after the turn negative, but need regular TCT and HPV examination. High-risk HPV51 positive, the viral infection lasts for more than 2 years, and the viral load is relatively high, the local environment of the cervix is poor, and cervical biopsy is done to find precancerous lesions or even cervical cancer, this situation of high-risk HPV51 positive usually does not heal itself, but some of the diseases can be cured. Usually, precancerous lesions are more likely to be cured, while cervical cancer has a higher clinical cure rate when detected early, but a lower cure rate when detected late. In daily life, we should pay attention to eat less spicy, greasy and stimulating food. Do not have intercourse during menstruation and pay attention to menstrual hygiene.