The toxic reaction of magnesium sulfate is mainly manifested as the suppression of central nervous system, which leads to the corresponding symptoms, such as dizziness, nausea, vomiting, mental concentration, hand and foot incoordination, nystagmus, blurred vision, etc. It may also have an inhibitory effect on the tendon reflexes of limb muscles, resulting in the symptoms of weakened tendon reflexes. If the symptoms are serious, there will be changes in the state of consciousness, such as blurred consciousness or even coma, shock, central respiratory depression and lead to life-threatening. If it is oral magnesium sulfate poisoning, there are also symptoms related to the digestive tract, commonly nausea, vomiting, abdominal pain, diarrhea and other manifestations.