Yellow liquid in the second year after endometrial cancer surgery is usually abnormal, which may be caused by inflammation or cancer recurrence. If the patient is accompanied by vulvar itching and yellow fluid with odor, it may be caused by vaginitis and other reasons, mostly due to the invasion of external pathogens into the vaginal mucosa, which is usually abnormal. If the patient also has vaginal bleeding without vulvar itching, it mostly suggests that it may be caused by recurrence of endometrial cancer, and once combined with infection, the yellow discharge is mostly accompanied by bad odor, which is also abnormal. If the patient has yellow liquid in the second year after endometrial cancer surgery, it is recommended to consult doctor in time, and under doctor’s guidance, improve relevant examination, clarify the cause of the disease, and target treatment.