Sildenafil is Sildenafil Citrate, Sildenafil Citrate should be used with caution after taking Irbesartan, and should be used in accordance with medical advice. Irbesartan is an angiotensin II receptor antagonist, which has the effect of lowering blood pressure. Sildenafil citrate tablets have a vasodilatory effect, can play a certain role in lowering blood pressure, the instructions pointed out that the combination of this product and antihypertensive drugs may cause symptomatic postural hypotension, manifested as vertigo, dizziness and dizziness. Therefore sildenafil citrate should be used with caution after taking irbesartan. Irbesartan can be used in primary hypertension, type 2 diabetic nephropathy combined with hypertension. Adverse reactions can be seen as dizziness, nausea, vomiting, fatigue, and upright hypotension. The drug is contraindicated in people who are allergic to the components of the product, in the 4th to 9th month of pregnancy, and during breastfeeding. Sildenafil citrate is used for erectile dysfunction and to treat pulmonary hypertension in adults. Adverse reactions can be seen such as infection, anemia, fluid retention, insomnia, anxiety, and headache. The drug is contraindicated in people who are allergic to the product, severe liver damage, recent myocardial infarction, and initial severe hypotension. The use of both drugs should be rationalized under the supervision of a doctor.