Total excision surgery is generally used to treat more advanced penile cancer, proximal penile severance injury or gunshot injury, cancer that has spread to the scrotum and other diseases. 1. advanced penile cancer: it is a kind of malignant tumor occurring in male penile area, in which nodules or lumps can be touched on the mucous membrane of the head of penis, coronal groove and inner plate of prepuce, and patients with advanced disease have distant metastasis, which need to undergo total excision surgery. 2. Proximal cut wound or bullet wound: Proximal cut wound or bullet wound, resulting in the complete separation of the entire penis or basically separated from the body, patients who are unable to perform or unable to perform penile reimplantation surgery need to undergo total necrosectomy. 3. The cancer has spread to the scrotum: these patients need to have the penis and scrotum removed together. It is recommended that patients should consult the doctor for timely examination and standardized treatment if they feel unwell, so as to avoid delaying or aggravating the condition.