High low pressure in middle-aged people requires medication such as furosemide, terazosin, nifedipine, enalapril, irbesartan, metoprolol, etc. if hypertension is diagnosed. If the low pressure is transiently elevated, no medication is needed. Low pressure refers to diastolic blood pressure, under normal circumstances, diastolic blood pressure should be less than 80mmHg, if greater than or equal to 90mmHg is considered high blood pressure. If middle-aged people with high diastolic blood pressure diagnosed as hypertension, if the early when the control of diet, exercise is ineffective, patients need to comply with medical advice to use hydrochlorothiazide, furosemide and other diuretics. If the blood pressure progresses to severe, it needs to be combined with beta-blockers such as metoprolol and atenolol. There are also alpha receptor blockers such as prazosin and terazosin. For those who want to stabilize moderate hypertension and above, on top of the previous drugs, angiotensin-converting enzyme inhibitors such as enalapril and benazepril, as well as angiotensin II receptor antagonists such as irbesartan and temesartan, should be used on a regular basis as prescribed by the doctor. To summarize, it is recommended that middle-aged people have annual medical checkups on time, strengthen their daily life management, and actively cooperate with doctors for treatment when hypertension appears in the checkup.