The first person to apply the word “plastic” to medicine was Dr. Zeis, who used it in his book “Handbuch der Plastischen Chirurgia” published in 1838 to describe the surgeon’s ability to repair or modify parts of the body that had been damaged by disease or trauma. or trauma to a body part. Although the term “plastic surgery” only appeared in the nineteenth century, the concept of plastic surgery has been developing since thousands of years ago. The matter of plastic surgery has evolved with the development of technology and the iteration of the project, and there are many names that have been developed so far, so in order to better understand plastic surgery, let’s look at the origins of these projects. “Plastic surgery project” origin 1, type A botulinum toxin Origin: 1986 In the 19th century, war mongers used botulinum toxin as a biological weapon, it can block the transmission of nerve signals, so that people appear dizzy, breathing difficulties, muscle weakness and other symptoms. It was also botulinum toxin type A, a neurotoxin that has the effect of blocking nerve signal transmission, that was used peacefully as the times progressed. In 1986, a Canadian ophthalmology professor discovered that botulinum toxin could make the wrinkles under the patient’s eyes disappear, and he announced it to the outside world, sparking the so-called revolution in the history of cosmetology, and since then botulinum toxin type A has been widely used. In the medical community, Botox is the drug of choice for the treatment of strabismus, cerebral palsy muscle ankylosis, migraine headaches, and other conditions, in addition to its cosmetic benefits. Of course, the amount of botulinum toxin used for cosmetic and therapeutic purposes in the medical field is extremely tiny, generally only a few dozen units are injected (one unit of botulinum toxin is the limit dose that a 20 gram mouse can tolerate), and people generally have a good tolerance, which is very safe. 2.Hyaluronic acid Origin: 1934 In 1934, ophthalmology professor Meyer and others first isolated hyaluronic acid from the vitreous humor of bull’s eye and analyzed its structure. It was named Hyaluronic acid (hyaluronic acid) because it was extracted from Hyaloid (vitreous humor). In subsequent studies, scientists found that it is a straight-chain macromolecular polysaccharide formed by the polymerization of two monosaccharides, glucuronic acid and acetylglucosamine, with each other. In aqueous solution, hyaluronic acid’s sugar chains are cross-linked to form a network, making it act like a sponge that can absorb and retain large amounts of water. Injectable hyaluronic acid was approved by the FDA in 2003 for skin wrinkle reduction. 3. Mesotherapy Origin: 1952 Mesotherapy, also known as mesotherapy, originated in France and was first created and applied clinically by Dr. Michel Pister in 1952. Mesotherapy is a mixture of different therapeutic agents that are injected into the patient’s mesoderm and used to treat general disorders in the early days. In 1987, the French Ministry of Health officially included mesotherapy as one of the legal transmission medical treatment programs. In 1988, Italian dermatologists discovered that injecting soy lecithin (PTC) under the skin has a lipolytic and anti-cellulite effect, and thus Mesotherapy officially entered the market of beauty, rejuvenation and slimming. Over the years in the countries of the doctor’s continuous efforts and exploration, so far the world, including Europe and the United States, Central and South America, there are more than 15,000 cosmetic plastic surgeons trained to use and promote this therapy, in recent years in the world of medical aesthetic market is gradually forming a trend. 4, autologous fat transplantation Origin: 1893 In 1893, German doctor Franz Neuber cut the upper arm small fat block to fill the cheek depression. In 1895, Karl Czerny, a German doctor, transplanted fatty tumors from the waist to the breast to reconstruct the deformity after the removal of benign breast masses. In 1911, Bruning used a syringe to inject a small amount of fat to correct soft tissue depressions. In 1965, the liquid silicone injection technique was introduced and thus became popular, and the autologous fat free grafting technique cooled down. The use of autologous fat grafting in rejuvenation began in the late 1970s, when the development of fat aspiration techniques made it easy to obtain fat tissue and autologous fat injections began to heat up again. French doctor Illouz first used a large number of autologous fat particles for transplantation. 5, rhinoplasty Origin: 1911 As early as 1911, Kolle had injected paraffin oil for rhinoplasty. Later, Joseph in Germany used ivory to augment the nose and achieved good results. John Orlandopoe (1887) in the United States performed the first nasal reduction. And a lot of work in rhinoplasty is Jacgues Joseph (1865 ~ 1934) in Paris, France, he carried out the removal of the hump of the nose, the narrowing of the nasal dorsum and the transformation of the lower part of the nose, creating a series of new methods. 6.Breast augmentation Origin: 1895 As early as 1895, Czerny augmented the breasts of an actress who had her bilateral mammary glands removed due to chronic cysts with an autologous abdominal wall fat free graft. The fat was absorbed, but the move was a bold exploration of breast augmentation. Gesun (1899) was the first to use liquid paraffin wax for intra-mammary injection to enlarge the breast, with good results recently, but serious complications soon appeared. Later, dermal grafts and local flap transfers were used to increase the volume of the breast. In the 1950s, Pangman in the United States applied a porous sponge with a polyethylene capsule to prevent fibrous tissue from growing into the sponge, but this caused serious complications. Cronin and Gerow (1963) designed an artificial breast prosthesis with a silicone capsule filled with liquid silicone, which was popular for its shape and feel. Whether people think plastic surgery is good or bad, it is a major advancement in technology, and the advent of the “face” era is also a major trend in social development. The basis of all this is “safety”, the development of plastic surgery is also in the direction of safer means and technology iterative update!