Face pain after applying facial cleanser is considered to be a case of cosmetic dermatitis or allergic dermatitis, which is mainly caused by facial allergy after facial cleanser stimulates the facial skin causing local capillary dilation and increased inflammatory exudation. In superficial vascular areas, leukotrienes and histamines accumulate and cause skin irritation, resulting in a stinging sensation. The clinical treatment can be oral levocetirizine hydrochloride with olopatadine hydrochloride tablets and topical zinc oxide borate ointment with pimecrolimus cream to apply the treatment. You should avoid using facial cleanser again and use lukewarm water to cleanse your face.