Dampness in the anus may be caused by perianal eczema, anal fistula, rectal prolapse and other factors. 1. Perianal eczema: usually due to a variety of factors such as gastrointestinal dysfunction, friction and other non-infectious diseases of the anal opening and the surrounding skin, during the onset of the disease, there may be secretion outflow, which leads to the phenomenon of anal moisture. Patients can use vitamin B, sodium thiosulfate solution and other drugs under the guidance of the doctor for treatment. 2. anal fistula: usually refers to the abscess around the anorectum after the collapse of the sequelae of the lesion, the occurrence of anal fistula will lead to increased secretion in the anal area, resulting in the phenomenon of anal moisture. Patients can follow the doctor’s instructions to use potassium permanganate solution sitz bath and other drugs or surgical resection for treatment. 3. Rectal prolapse: mainly due to the increase of abdominal pressure, dysplasia and other factors lead to the displacement of the rectal wall partially or completely downward, with the aggravation of the condition, there will be mucus outflow, thus the phenomenon of anal wetness. Patients can be treated with medications such as quinine hydrochloride urea aqueous solution and phenol vegetable oil under medical supervision. Moisture in the anus may also be related to hemorrhoids and other diseases, it is recommended that patients seek medical examination in a timely manner, and under the guidance of the doctor, after clarifying the cause of the disease, to take the cause of the treatment.