Chronic sinusitis eat roxithromycin general course of treatment is not less than 12 weeks, but the specifics vary from person to person, and adverse reactions should be discontinued in time. Chronic sinusitis can be applied to macrolides, macrolides should be used in conventional drug therapy is not effective, no eosinophilia, serum total IgE level is not high, and allergen test negative chronic sinusitis patients. Clinical recommendations are small doses of 14 yuan ring macrolides for long-term oral administration for a period of not less than 12 weeks. Roxithromycin belongs to the class of macrolides and can be used to treat chronic sinusitis with a course of treatment of not less than 12 weeks, usually in small oral doses, subject to doctor’s recommendations. Taking Roxithromycin may cause abdominal pain, diarrhea, nausea, vomiting, decreased liver function, dizziness and headache and other adverse reactions, if similar symptoms occur, it is recommended to stop using the drug and go to the hospital for examination. The drug should be used with caution in people with liver insufficiency, pregnant women and lactating women. The drug is contraindicated for those who are allergic to roxithromycin, erythromycin or other macrolides.