Some patients with multiple lung adenocarcinomas in both lungs can be treated by surgery, radiotherapy, chemotherapy and other ways. Multiple lung adenocarcinoma of both lungs can be divided into four stages: Ⅰ, Ⅱ, Ⅲ and Ⅳ. Stage I is the early stage, in which patients may not have obvious symptoms and the tumor has not metastasized. Surgical treatment is the mainstay, such as lobectomy, hilar mediastinal lymph node dissection and so on. Stage II is the middle stage, the cancer cells have metastasized to the lymph nodes near the hilum, and it can be treated by surgery such as lobectomy and double pneumonectomy. Stage III is the middle and advanced stage, the cancer cells have metastasized to the patient’s mediastinal and extrapulmonary lymph nodes, and neoadjuvant chemotherapy and surgical treatments, such as lobectomy and systematic mediastinal lymph node dissection, are generally recommended. Stage IV is the advanced stage, with pleural metastasis and systemic metastasis, etc. Radiation therapy can be used. Which treatment mode should be adopted for patients with multiple lung adenocarcinoma in both lungs needs to be judged by doctors according to the patients’ own conditions, and it is recommended that patients actively cooperate with doctors’ treatment to control their conditions and improve their quality of life.