Stuffy acne hardness can be drained by oral antibiotics, topical medications, skin cleansing, and physical therapy. 1. Oral antibiotics: Stuffy acne, also called acne, is an inflammatory disease of the sebaceous glands of the hair follicles. Most severe acne may develop hard nodules. Patients are advised to take oral antibiotics for treatment, such as doxycycline tablets and isotretinoin soft capsules. 2. Topical medication: It is recommended that patients apply hot compresses for five minutes every night to the localized skin where the acne nodules are located, and then apply cumexin cream ointment or retinoic acid ointment or adapalene gel to promote the receding of acne, as well as topical mupirocin ointment or fusidic acid ointment. 3. Clean skin: patients are advised to keep their face clean, and can use warm water and facial cleanser to wash the affected area daily, so that the dull acne nodules may be discharged. 4. Physical therapy: For whiteheads developing into blackheads, you can use a sterile acne needle to press out the pimples, then use boric acid solution to soften the sebum with hot compresses, gently press, you can discharge the dull acne nodules, and then apply anti-inflammatory creams. It is recommended that patients do not wear makeup during the treatment period, and do not eat spicy stimulating food, keep the local skin clean and hygienic. Boring acne nodules on the skin, to follow the doctor’s instructions to use medication.