Blood in urine after one and a half years after colon cancer surgery should be urologically evaluated for the cause and then targeted treatment. Bleeding hematuria one and a half years after colon cancer surgery has no correlation with surgery itself, so surgical injury causing hematuria is not considered. The common causes of hematuria include urinary tumor, inflammation, trauma, stone, peripheral tumor invasion and so on. Hematuria may also occur when the recurrent metastatic lesion of colon cancer invades ureter and bladder after surgery, in which case CT examination should be carried out to evaluate the relationship between the lesion and the surrounding organs. If it can be surgically resected, it should be surgically resected first, and if it cannot be surgically resected, chemotherapy, radiotherapy, targeted therapy and other treatments can be considered.