Indigestion in children is mostly functional in origin and is the most common clinical syndrome in pediatrics. Its pathogenesis is not clear, but is generally considered to be related to gastrointestinal dysfunctional disorders, abnormal visceral plant nerve function, abnormal gastric acid secretion, Helicobacter pylori infection and psychosomatic factors. The main clinical symptoms are upper abdominal discomfort, bloating or pain, decreased appetite, early satiety, belching, nausea and vomiting. In addition, many children will have a combination of psychosomatic symptoms such as neurosis and anxiety disorders, and the related symptoms can be recurrent and can generally manifest as single or concurrent episodes. These symptoms can lead to malnutrition and growth retardation if they recur for a long time. In general, it is recommended to improve the child’s lifestyle and diet structure, such as meat and vegetables, no picky eating, no partial eating and change the bowel habits. In addition, oral medications to regulate intestinal flora such as bifidobacterium and lactobacillus can be taken (for specific medications, please combine with clinical practice, subject to the guidance of the doctor’s interview). Again, Chinese medicine is also effective in the treatment of pediatric indigestion, which is generally considered to be caused by the weakness of the spleen and stomach and abnormal transportation and digestion. In conclusion, there are many causes of indigestion in children and various factors affecting them, so specific analysis of the problem and symptomatic treatment.