If the cervix was infected with high-risk HPV before total hysterectomy, it will definitely become negative for HPV after total hysterectomy. However, it should be noted that the vaginal stump may be re-infected with high-risk HPV again, which is mainly due to the presence of sexual intercourse. Therefore, even though the hysterectomy is done, gynecological checkups should be done regularly to find out if the vaginal stump is infected with high-risk HPV. If there is no high-risk HPV infection after the examination, you will have to be examined once a year, and if you are negative for three consecutive years, you can be examined again in three years. After complete removal of the uterus the cervix becomes 100% negative for localized HPV because the cervix has been removed and has become a discrete specimen, so there is no chance of further infection.