White vinegar is a kind of flavoring agent, does not have the role of drugs, usually can not be used for spot removal, need to use standardized drugs or physical therapy. 1. The main component of white vinegar is acetic acid, although there is a certain corrosiveness, but there is no scientific evidence that white vinegar has the effect of removing spots. Pigmentation spots are pigmented spots with different colors between the lesion area and the surrounding skin, such as freckles, chloasma, age spots, etc., which need to be treated according to specific conditions. 2. Different types of spots differ in treatment, such as freckles which can be treated by physical means such as strong pulse light and liquid nitrogen freezing. Melasma can be treated with 2%~5% hydroquinone cream, azelaic acid and other drugs with exfoliation effect. Age spots can be treated with laser, electrocautery, freezing and other physical treatments. It is recommended that patients go to regular hospitals for consultation and follow the doctor’s instructions for scientific and reasonable medication and treatment.