Blood tests 1. Routine blood tests: to check for abnormal indicators, to indicate changes in the disease and to monitor adverse drug reactions. 2.Liver and kidney function: to check the function of liver and kidney, suggesting disease changes as well as whether the drugs are damaging the internal organs. 3.Erythrocyte sedimentation rate (ESR): referred to as blood sedimentation, normal reference value: 0-15mm/h for adult male and 0-20mm/h for female. The higher the ESR, the more the disease is still active and the less serious it is, excluding other causes. A decrease in blood sedimentation indicates that the disease is under control.? In rheumatic immune diseases, ESR is higher than 25 to be meaningful. 4.C-reactive protein (CRP): normal value <8MG/L, high CRP, indicating the presence of infection, trauma, inflammation, disease is still in the active stage. 5.Anti-streptococcal hemocyanin "0" (ASO): normal value is less than 1:500, positive indicates that the body is infected with hemolytic streptococcus, which can lead to rheumatic fever. 6, rheumatoid factor (RF): RF is common in a variety of rheumatic diseases and acute and chronic inflammatory diseases. Therefore, you can't think you are rheumatoid arthritis based on a positive RF alone. However, if the RF titer is high, multiple positive determinations, multiple positive determinations, then the likelihood of rheumatoid arthritis is higher. Anti-cyclic citrullinated peptide antibody (CCP), anti-keratin antibody (AKA), anti-perinuclear factor (APF), anti-RA-33 antibody, anti-Sa antibody: These are commonly found in patients with rheumatoid arthritis, especially in the early stages of rheumatoid arthritis, and are important for the diagnosis and prognosis of the disease. 8.Anti-nuclear antibody (ANA): Positive is common in many diseases. A positive ANA in high titers is highly suspicious of SLE, while a negative ANA can almost certainly exclude the diagnosis of lupus. 9. Anti-ds-DNA antibodies: almost exclusively seen in patients with SLE. It is also closely related to active lupus nephritis. The higher the antibody titer, the higher the rate of disease activity. 10. Anti-Sm antibody: almost only seen in patients with SLE. It is a marker antibody for SLE. However, not all patients with lupus show positivity. 11.Anti-SS antibody and anti-SSB antibody: seen in many diseases, but have greater significance for the diagnosis of dry syndrome. 12.HLA-B27: It is a genetic test and has significance for the diagnosis of ankylosing spondylitis. Imaging examinations 1. X-ray examination: usually choose the area with the most severe symptoms. If the local symptoms are not typical, the doctor will choose the common areas of the disease to be photographed based on the identified direction of consideration, such as rheumatoid arthritis, often choosing the hands and wrist joints; ankylosing spondylitis, often choosing the bilateral sacral joints and hip joints. Regular X-ray examinations can be performed before and after to determine whether the disease is under control after treatment and to judge the effectiveness of treatment. 2, CT examination: higher resolution, conducive to the early detection of disease, can be found in the X-ray can not show lesions. It is important for the diagnosis of diseases. 3.Magnetic resonance imaging (MRI) and B-ultrasound examination: it can show the internal lesions of the joints such as cartilage, synovium and joint effusion clearly, which is important for the early stage of the disease, and also has some significance for the judgment of the disease.