Thinning of the RNFL refers to the thinning of the retinal nerve fiber layer, usually due to glaucoma, retinitis pigmentosa and other causes. The visual information formed by photoreceptor cells in the retina needs to be converged to the optic nerve through nerve fibers sent from ganglion cells, and then conducted to the visual center of the brain to form vision, and all the nerve fibers together constitute the retinal nerve fiber layer. When there are retinal lesions, such as glaucoma, retinitis pigmentosa and other diseases, it will lead to thinning of the retinal nerve fiber layer, and at this time, OCT examination HRT-2 examination can be found that the thickness of the RNFL is thinning. Thinning of the RNFL thickness should be further treated after an interview with a physician.