High alkaline phosphatase can be categorized into physiological high, such as in the growth and development of children, without special treatment; can also be seen in pathological diseases, such as liver and gallbladder diseases, bone diseases, hyperparathyroidism, etc., should be treated for the cause, liver and gallbladder diseases should be antiviral treatment or surgery to relieve biliary obstruction, etc.; bone diseases and hyperparathyroidism surgical treatment.
1. Physiological: During the growth and development period of children, high alkaline phosphatase can occur due to the growth of bones, which belongs to the physiological high, and can be restored to normal by itself, so there is no need to worry too much.
2. Hepatobiliary diseases: chronic hepatitis, biliary obstruction, etc. lead to alkaline phosphatase excretion obstruction and elevation. The common cause of chronic hepatitis is hepatitis B virus infection, which should be treated with antiviral therapy and hepatoprotective therapy; biliary obstruction should be treated with water fasting, gastrointestinal decompression and surgery to relieve the obstruction.
3. Bone disease: bone tumor, rickets, malignant tumor bone metastasis, etc., can appear elevated alkaline phosphatase, should go to the orthopedic consultation orthopedic surgeon to evaluate the discretion of surgical treatment.
4. Hyperparathyroidism: hyperparathyroidism can have increased osteoclast activity, increased blood calcium, decreased blood phosphorus, alkaline phosphatase is elevated, the treatment can be applied to calcitonin, cinacalcet and other medications, but also surgical treatment.
Alkaline phosphatase high in the exclusion of physiological causes is recommended to timely consultation, under the guidance of the doctor for targeted treatment.