The normal value of platelets is (100~300)×10⁹/L. Platelets of 398×10⁹/L are on the high side, and the reasons for the high side include physiologic increase, reactive increase, and primary thrombocythemia.
1. Physiological increase: Platelet count fluctuates during the day, higher in the afternoon than in the morning, strenuous exercise, after a full meal, etc. can also lead to an increase in platelets. Besides, the season also affects the platelet count, which is generally higher in winter than in spring. This is a normal physiological phenomenon.
2. Increased reactivity: Inflammation, infection, trauma, etc. can lead to increased platelet reactivity, such as rheumatoid arthritis, acute rheumatic fever, tuberculosis, chronic lung abscess, osteomyelitis and so on.
3. Primary thrombocythemia: it is a chronic myeloproliferative disease, which is mainly characterized by continuous proliferation of bone marrow megakaryocytes and thrombocytosis with abnormal function.
There may be other reasons for elevated platelets, so it is recommended to go to the hospital and clarify the cause of elevated platelets under the guidance of the doctor.