Mucosal elevation of the ascending colon may be colon polyps, benign tumors of the colon, colon cancer, and so on. 1.Colon polyps: colon polyps are elevated lesions of colon mucosa, which can be divided into tumor polyps and non-tumor polyps. Most patients with colon polyps often have no obvious symptoms, often found in intestinal endoscopy, can be manifested as intestinal bleeding, abdominal pain, diarrhea, intestinal obstruction, etc., and some of them can also be malignant. 2. benign colon tumor: the common ones are colonic smooth muscle tumor and colonic mesenchymal tumor, which often invade the intrinsic muscle layer and submucosal layer, and can be clinically cured by endoscopic mucosal dissection. 3. Colon cancer: colon cancer is a malignant tumor originated from the mucosal epithelium of colon, early asymptomatic, later can be manifested as blood in the stool, emaciation, change of stool properties, anemia and so on, should be actively treated. Patients with elevated mucosal bulge of ascending colon should go to the hospital for further clarification of the cause and treatment under doctor’s guidance.