The causes of hyperechoic nodules in the left clavicle include supraclavicular lymphadenitis and lipoma. 1. Lymphadenitis: patients may have obvious enlargement on the clavicle, and obvious nodules can be touched on the clavicle area, and it is necessary to take blood tests, such as routine blood test and C-reactive protein test. If it is diagnosed as lymphadenitis, it is necessary to carry out anti-infection treatment under the guidance of doctor, and the lymphadenitis will disappear after treatment. 2. Lipoma: if there is no obvious symptom of small size lipoma, no need to deal with it, observation and treatment can be enough, when the lipoma gradually increases, the nodule can be touched in the clavicle area, which will cause local pain after stimulating the surrounding tissues, and then surgical resection is needed. Therefore, the hyperechoic nodular shadow in the left clavicle needs to be examined and treated after the etiology is clarified.