Cough with occasional blood in sputum caused by lung cancer is considered to be caused by the tumor mass itself breaking and bleeding or invading blood vessels, and timely treatment is needed to improve the symptoms. If lung cancer is not effectively controlled, malignant proliferation of tumor cells will compress and invade bronchial tubes, stimulate mucous membrane of trachea and damage blood vessels of trachea, which will lead to coughing with blood in sputum, and patients need to choose surgical treatment, radiotherapy, chemotherapy and targeted therapy according to the seriousness of the disease, and at the same time can apply medicines of hemostasis for symptomatic treatment. When the tumor is limited and the patient is in good health, resection of the lesion can be considered to relieve the trachea from compression and invasion; for unresectable tumor foci or when the patient is not in good health, radiotherapy and targeted therapy can be used to shrink the lesion and improve the prognosis of the disease, and the specifics of which can be obtained by consulting with a professional physician.