The more recognized time for fetal anomaly screening in China is 22-26 weeks of gestation, which mainly observes the general anatomy of the fetus and screens out fetuses with problems, such as cleft lip and palate, severe spina bifida, severe chest and abdominal wall defects and children with limb defects, such as those with upper or lower limb defects, which are more appropriate to be done at this time. All pregnant women, as well as obstetrics teachers, need to understand that fetal growth in the mother’s body is a gradual process. In addition to screening for fetal malformations at 22-26 weeks, some structures of the fetus, such as urinary and digestive problems, may not be detected until late pregnancy, and it is recommended to do additional screening for fetal malformations at 32 weeks, and then observe the fetus for urinary or digestive problems.