Patients with chest pain after smoking may be caused by inflammation in the lung, tuberculosis, lung tumors and other diseases. Patients with chest pain after smoking are advised to actively seek medical advice, quit smoking, improve relevant examinations, and assess what kind of disease is causing the chest pain, and different diseases are treated differently: i. Patients with inflammation in the lung need to identify the causative organism and take corresponding treatment according to the causative organism, such as bacterial infections need to be treated with antibiotics, and atypical pathogenic infections can be treated with antibiotics. Atypical pathogenic bacterial infections can be treated with macrolide antibiotics or quinolone antibiotics; ii. Patients with pulmonary tuberculosis need anti-tuberculosis treatment, and can use isoniazid, rifampin, pyrazinamide, streptomycin and other related anti-tuberculosis drugs; iii. Patients with lung tumors should be evaluated surgically, and surgical treatment should be performed if there are indications for surgery, and radiotherapy, chemotherapy, and target cell drug treatment can be considered if there are no indications for surgery.