When perioral acne or blistering occurs in adolescence, it is important to analyze whether it is herpes or acne due to the higher secretion of sebaceous glands. In most cases, there will be herpes around the mouth, which is what the people call a fire, or if there has been a recent anxiety and fire, the body’s resistance will drop slightly and the herpes simplex virus will enter the body and begin to multiply, causing more localized herpes to rise. The perioral area including to the nose to the perioral area is the danger triangle, where the sebaceous glands of the hair follicles are richer and if not carefully cleaned, acne and pimples will also appear, so in this case it is necessary to keep the local skin as clean as possible, clean the pores of the sebaceous glands and clean them regularly. So for perioral acne, it is important to analyze whether it is herpes or acne, and its treatment is not exactly the same. But in general it is hoped that keeping the area clean, being happy, and not getting anxious and inflamed will all help a lot.