How long it takes to remove the plate from the humerus under general anesthesia depends on the location of the fracture and the patient’s specific situation, and cannot be generalized. If a humeral fracture is treated with internal fixation of the plate, removal of the plate screw internal fixation can be considered if the fracture heals. If the humerus fracture is located proximally, it is generally easier to remove the internal fixation. It takes about 45-60 minutes to remove the plate under general anesthesia, but the exact time varies from person to person. If the humerus fracture is located in the middle and lower segments, it is more difficult to remove the internal fixation and there is a high risk of injury to the radial nerve and other important structures, so it is usually not recommended to remove the internal fixation plates from the middle and lower segments of the humerus. If removal is insisted, the timing of plate removal under general anesthesia needs to be determined on a case-by-case basis and cannot be specified. In addition, it is recommended that the patient have an X-ray review before removing the plate to make sure that the fracture line has disappeared and complete bony healing has been achieved before the internal fixation removal can be done, otherwise it may easily lead to secondary displacement of the fracture severed end.