It is possible for leukemia M4E0 to achieve a state of long-term remission with chemotherapy or to undergo allogeneic hematopoietic stem cell transplantation to prolong survival and reduce the chance of relapse. Leukemia M4E0, or acute granulocytic-monocytic leukemia, is characterized by a large number of abnormally proliferating naïve cells of the neutrophilic and mononuclear lineages. 1. The relative prognosis of leukemia M4E0 is better. Generally speaking, the prognosis is positively correlated with the effect of chemotherapy, and if the patient is older or has more underlying diseases, the weaker intensity of chemotherapy will affect the prognosis of leukemia. If the patient has a relatively good fusion gene and is also in good physical condition, many patients can achieve long-term survival after treatment. Chemotherapeutic drugs include cytarabine and Zoerythromycin. 2. If hematopoietic stem cell transplantation can be performed, the survival rate can also be further improved. Once leukemia, should go to the regular hospital in a timely manner, to identify the type and under the guidance of the physician for targeted treatment, M4E0 part of the patient after standardized treatment can achieve long-term remission.