High creatinine but normal cystatin C needs to be identified and treated according to the cause. The causes can be categorized into physiological factors and pathological factors, the former is commonly seen in excessive meat consumption or heavy exercise, the latter can be seen in some extra-renal diseases such as hypertension, etc., and may also be seen in some patients with chronic renal failure.
1. Physiological factors: some patients with high creatinine may be due to the high muscle content of the patients themselves, or usually eat more meat, exercise more caused by routine urinalysis and ultrasound of the urinary system and other relevant examinations do not see any abnormality, and clear renal disease, cystatin C can be normal, at this time there is no need for special treatment.
2. Extra-renal diseases: cystatin C is an indicator of glomerular filtration function, and its sensitivity is often higher than creatinine. If cystatin C is normal and creatinine is high, it usually means that there is no problem in kidney, and it is mostly caused by extra-renal diseases. For example, hypertension patients with unstable blood pressure or overwork may lead to high creatinine in the body, and need to control blood pressure and other causative treatments, such as nifedipine and other drugs.
If patients find high creatinine, it is recommended to go to regular hospitals in a timely manner, improve the examination to clarify the cause of the disease, and then give targeted treatment or treatment under the guidance of the doctor.