Long-term oral administration of Saccharomyces boulardii is generally not recommended. Saccharomyces boulardii is a biological antidiarrheal agent that can be used to treat infectious or non-specific diarrhea and irritable bowel syndrome in children or adults. It should be noted that the drug should not be used by people who are allergic to the drug, fructose intolerant, congenital galactosemia, etc.; after the use of the drug, you may experience persistent constipation, urticaria, dry mouth and other adverse reactions. The course of Saccharomyces boulardii is usually 3 to 7 days, if necessary, under the guidance of a doctor to extend the duration of the drug, generally in the relief of symptoms can be considered to stop the drug; some patients may experience adverse reactions after using the drug, once the long-term use of the drug may exacerbate the adverse reactions, so it is not recommended that patients use the drug for a long period of time. Patients who need to use Saccharomyces boulardii treatment should be under the guidance of a doctor to use the drug, not blindly used on their own.