There is no clear clinical data on the efficacy and effects of Rhizoma Dioscoreae Root Wine, but Rhizoma Dioscoreae Root Wine with other Chinese herbs can have the effect of clearing away heat, detoxifying, and killing worms. It is also known as “sheep’s hoof root”, and it is recorded in “Zhu Renkang Clinical Experience Collection” that sheep’s hoof root can be paired with other traditional Chinese medicine to make sheep’s hoof root wine. Its main ingredients are sheep’s hoof root, betel nut, Momordica charantia, sea tung bark, hibiscus bark, made Chuanwu, white fresh skin, bitter ginseng, Qianjinzi, dibasic, fenugreek, snakebeds, snake clothes, and big maple seeds. Sheep’s foot root wine mainly has the efficacy of clearing away heat and detoxification, killing insects, and can be used for the treatment of ringworm, tinea cruris, and neurodermatitis. When using the medicine, you need to dip a brush into the wine and apply it externally. It is recommended that the patient under the guidance of the doctor reasonable use of soil rhubarb root and other Chinese herbs for wine, and strictly follow the doctor’s instructions for medication.