Cranial repair is a common neurosurgical procedure to repair the skull in response to traumatic brain injury resulting in a skull defect. Patients with cranial defects often have a heavy burden of insecurity and can cause syndromes such as headache, dizziness, and fear of vibration. The longer the cranial defect, the higher the incidence of cranial defect syndrome and secondary brain damage. In order to restore the cranial cavity confinement, keep the physiological intracranial pressure stable and reduce the cranial defect syndrome. In order to restore the cranial cavity, keep the physiological intracranial pressure stable, and reduce the cranial defect syndrome, cranial repair should be performed for cranial defects with a diameter of 3 cm or more without muscle coverage and without contraindications. For children with cranial defects, generally speaking, cranial repair is possible after 3 years of age if cranial defects occur. Restoring the integrity of the cranial cavity can improve brain tissue development and promote neurological recovery. Currently, polyetheretherketone PEEK is an ideal material with excellent performance. We use peek cranial repair, peek material is a polymer material, preoperative three-dimensional reconstruction according to the patient’s cranial CT data, highly restore the anatomical structure of the skull, accurate anastomosis of the defect area, and this material can be fused with the autologous cranial bone, integrated, all the performance is very good, is a very good cranial repair material.