Splenomegaly for almost 40 years is of no great concern, and the patient is considered to have physiologic splenomegaly. In physiologic splenomegaly, the spleen may be mildly enlarged, which generally does not require special treatment, and regular ultrasound review is sufficient. Moderate or severe enlargement of the spleen is often indicative of a pathologic cause, which needs to be diagnosed in conjunction with the patient’s clinical symptoms and other laboratory ancillary tests. The spleen is the body’s lymphatic organs, has a certain immune function, found that the spleen is enlarged, the first thing to rule out whether there is a pathological cause, it is recommended that when the spleen is enlarged, go to the gastroenterology department of the regular hospital in time, under the guidance of the doctor, so as to avoid delaying the condition.