Cold hands and feet and rapid heartbeat are often seen in the state of hypotensive shock. Hypotension often leads to peripheral hypoperfusion and the appearance of cold hands and feet, oliguria, anuria, and rapid heartbeat. Hypotension is commonly seen in pathologic states, such as acute hypotension, including acute drops in blood pressure caused by hemorrhage, infection, and shock hypersensitivity. In addition, for patients with organic heart disease, especially coronary heart disease, acute coronary syndrome, myocardial infarction, cardiogenic shock can occur, which leads to a drop in blood pressure and increased heart rate. It is recommended that for patients with cold hands and feet and accelerated heart rate, cardiac monitoring, monitoring blood pressure, oxygen saturation, heart rate and other conditions, and if necessary, give the application of vasoactive drugs to expand capacity and other comprehensive treatment.