It is possible to live a normal life with connective tissue disease. Connective tissue disorders are not contagious and mild connective tissue disorders do not adversely affect normal life and work. Connective tissue disease is a group of diseases with unknown etiology, involving multi-organ and multi-system connective tissue, mainly including lupus erythematosus, dermatomyositis, scleroderma, dry syndrome, rheumatoid arthritis, polyarteritis nodosa, and rheumatic fever, etc. This group of diseases has the characteristics of autoimmune diseases. This group of diseases has some features common to autoimmune diseases, such as multiple autoantibodies detectable in the serum and effective treatment with glucocorticoids and immunosuppressive drugs. Connective tissue diseases are non-infectious and are not directly related to pathogenic infections. Connective tissue disease is a disease of the rheumatoid immune system and requires long-term active and standardized treatment. Mild connective tissue disease also need to adhere to the combination of work and rest; when the condition is more serious, you need to take medication under the guidance of the doctor for treatment. During the period of illness, should maintain a positive and optimistic mentality, which will help the recovery of the disease. It is recommended not to be overly fatigued, overworked, and avoid staying up all night, so as not to aggravate the condition. At the same time, appropriate exercise can be used to enhance physical fitness and improve disease resistance, as well as to strengthen daily life care and prevent various infections. If there is any discomfort related to connective tissue disease, it is recommended to consult a doctor in time and follow the doctor’s instructions for standardized diagnosis and treatment.