Timosartan and amlodipine benzenesulfonate can generally be taken together. Timosartan is an angiotensin II receptor antagonist class of drugs, mainly to inhibit vasoconstriction. It is suitable for primary hypertension, renal insufficiency and combined hypertension, and can also inhibit ventricular remodeling, but still should pay attention to the drug is prone to hyperkalemia, the use of the drug need to closely monitor the blood potassium changes. Amlodipine benzenesulfonate is a calcium ion antagonist drug, can diastole vascular smooth muscle, reduce peripheral resistance, with anti-hypertension, relieve angina pectoris effect. It can be used in patients with hypertension and chronic stable coronary artery disease, but side effects such as headache can occur. The combination of the two drugs can reduce blood pressure to the desired level, and at the same time can protect the heart and kidneys, reduce the damage of high blood pressure on other organs, so timosartan and amlodipine benzenesulfonate can be taken together in general. All of the above medications should be used under the guidance of a doctor, avoid self-medication.