There are many diseases that can cause numbness in the thumbs and need to be treated for the cause. For example, if the numbness of the thumb is caused by vascular lesions in the lower extremities, such as venous thrombosis in the lower extremities, and is accompanied by pressure pain and swelling in the lower extremities, which affects walking, the treatment of this disease is mainly based on anticoagulation therapy, thrombolytic therapy, and surgery if necessary. In the case of spinal diseases, such as lumbar disc herniation or slippage, spinal stenosis and other compression of nerves resulting in numbness of the thumb, it is best to rest in bed, do traction therapy and physical therapy, and if necessary, surgery. In the case of peripheral neuritis of the foot caused by chronic diseases, such as diabetic foot, the first step in treatment is to lower blood sugar by taking glucose-lowering drugs or applying insulin, and taking nerve-nourishing drugs such as Micropod. Numbness can occur when the nerve in the thumb is compressed, such as when shoes are small or when high heels are worn.