Taking Vonorasan is usually not allowed to measure H. pylori immediately, otherwise the results will be affected. Vonorasan reversibly inhibits H+, K+-ATPase activity in a competitive manner with potassium ions, and is a new type of acid inhibitor, which can stay in the cellular parts of the gastric wall for a long time and inhibit the production of gastric acid, and can effectively inhibit the formation of mucosal damage in the upper part of the gastrointestinal tract. Studies have shown that voransen has a more potent and longer-lasting acid inhibition than proton pump inhibitors, with better H. pylori clearance, and there are already countries recommending voransen for the treatment of H. pylori infections, so taking voransen may affect H. pylori testing, and at least two weeks of acid suppression medication needs to be discontinued. Testing for H. pylori should also be done without taking any antibiotics for at least 4 weeks prior to the test and without taking any proton pump inhibitors such as omeprazole for at least 2 weeks prior to the test. Patients who are allergic to any of the ingredients in Vonorasan, patients being treated with atazanavir or rilpivirine are prohibited from taking any of the ingredients in Prohibited, and common adverse reactions include nausea, vomiting, and diarrhea. Specific precautions and tests related to the content should be carried out under the supervision of a doctor.