Pregnant women in the early stages of pregnancy must take folic acid, not only should they take folic acid in the early stages of pregnancy, but they should take folic acid in the three months before conception. The purpose of taking folic acid is to prevent neural tube malformations in the fetus and to reduce the chances of a fetus with cleft lip and palate being born. Generally, during the first trimester of pregnancy, the neural tube of the fetus is in a state of development, and if you don’t take enough folic acid during this period, it may lead to malformations in the development of the neural tube of the fetus. Of course, you should not blindly supplement folic acid, you should take a folic acid bioavailability test in the first trimester of pregnancy, and according to the results of the test, you should choose the appropriate dosage and time to take it, to avoid overdose and underdose of folic acid.