Trigeminal neuralgia because of the “pain” and cause patients to pay attention to the treatment of the disease, so that patients are more concerned about the disease. Trigeminal neuralgia is more common in women, and people who have experienced a lot of pain in their lives are more likely to suffer from trigeminal neuralgia attacks. As many people do not pay attention to the protection of facial nerves when they are young, trigeminal neuralgia attacks can easily occur as a result of the accumulation of the disease over the years. Trigeminal neuralgia attack is a disease with more hazards, and trigeminal neuralgia is also a disease with many sequelae, so we need to pay attention to trigeminal neuralgia disease. Trigeminal neuralgia attacks of pain will make the central nervous system in the state of excitement, sympathetic excitability increases, can be manifested as catecholamine secretion increases, glycogenolysis to enhance the role of trigeminal neuralgia, many trigeminal neuralgia patients do not dare to eat, the body is in the state of negative nitrogen balance, which is the after-effects of trigeminal neuralgia. Acute or prolonged pain will cause a series of physiological changes in the digestive system, nerves, circulatory system, and secretion of the respiratory system. Trigeminal neuralgia constant episodes of pain stimulation will cause the central nervous system secretion and a series of physiological activity changes. The best way to relieve trigeminal neuralgia is to use surgical microvascular decompression. Microvascular decompression surgery is performed under the microscope into the bridge cerebellar angle area to explore the trigeminal nerve course area, all the blood vessels and arachnoid strips that may produce compression are “loosened”, and these blood vessels are wrapped with an anti-adhesion membrane to isolate the nerves from the nerve roots. Once the responsible blood vessels have been isolated, the root cause of irritation disappears, and the hyper-excitability of the trigeminal roots disappears and returns to normal. In the vast majority of patients, pain disappears immediately after surgery and normal facial sensation and function is preserved without affecting quality of life.