Whether it is possible to take growth hormone with thyroid nodules should be judged according to the nature of the nodules, and growth hormone injection is not recommended if the nodules are at risk of malignancy. Growth hormone is a peptide hormone secreted by the anterior pituitary gland that promotes bone, muscle, and generalized growth, and is indicated for growth disorders due to insufficient endogenous growth hormone secretion. Growth hormone is contraindicated in critically ill patients with active tumors and/or active intracranial injuries, patients undergoing direct cardiac or abdominal surgery with complications, patients with multiple injuries or acute respiratory failure, and patients with proliferative or pre-proliferative diabetic retinopathy. Growth hormone should also be used with caution if there is a risk of malignancy in thyroid nodules. Whether patients with thyroid nodules can take growth hormone is recommended to be judged according to their condition under the guidance of a specialist.