In some patients, after laser treatment, the photothermal effect of the laser leads to tissue exudation and blisters (i.e., “blisters”) appear. If the diameter of the blister is large, it is recommended to puncture it; if the diameter of the blister is small, it is usually not necessary to puncture it. If the blisters appear after laser surgery, if the diameter is small, corn-like to mung bean size, generally do not need special treatment, the tissue fluid in the blisters can be absorbed, and can be eliminated by themselves, patients need to pay attention to postoperative care, avoid scratching, avoid touching the blisters with their hands and pay attention to the local disinfection, and at the same time need to pay attention to the sun protection. If there are larger blisters or blood blisters after laser, such as soybean size or even larger, the tissue fluid contained inside is more, it is difficult to be absorbed by itself, which can lead to higher skin tension, at this time, it should be punctured under the guidance of the doctor after aseptic disinfection to reduce the tension, and use iodine povidone disinfectant to disinfect the local area after puncturing, to avoid infection. It is recommended that patients with blisters on the skin after laser treatment should go to regular hospitals in a timely manner, and standardize the treatment under the guidance and advice of the doctor, and at the same time, they should usually take good care of themselves, pay attention to sunscreen, and keep the local area dry and clean, to avoid local infections.