Whether renal insufficiency without proteinuria is serious should be judged according to the cause of renal insufficiency. For example, urinary stones are relatively not serious, while those caused by glomerulonephritis are relatively serious. 1. Ureteral stenosis or stones: Obstructive renal insufficiency caused by ureteral stenosis or ureteral stones can have no proteinuria, and the decline of renal function can be delayed after treatment. 2. Glomerular diseases: such as IgA nephropathy, IgA nephropathy is a relatively common type of chronic glomerulonephritis, which can be manifested as asymptomatic hematuria, and the absence of proteinuria in the urine shows that there is no damage to the charge barrier of the renal basement membrane, and there is no loss of proteins, while there is a damage to the mechanical barrier, and a large number of red blood cells can appear in the urine. Patients need to pay attention to nutritional balance in the diet, control the intake of salt and protein, diet to light and easy to digest, avoid spicy and greasy food. Don’t stay up late, ensure enough rest and sleep, avoid overwork, quit smoking and drinking, and keep an optimistic and positive mindset. Patients with renal insufficiency without proteinuria need to go to a regular hospital, after a clear diagnosis under the guidance of the doctor for standardized treatment, so as not to delay the condition.